The iFish Study (registered at clinicaltrials.gov (NCT03765580)) was an 8-week randomized controlled trial which aimed to investigate the influence of fish consumption on PUFA concentrations amongst women of childbearing age, whilst accounting for FADS genotype which has been shown to influence PUFA status.
Participants were randomly assigned to one of three intervention groups and asked to consume a lunch dish containing 1, 2 or no portions of fish per week.
At baseline and post-intervention participants were asked to provide a range of biological samples alongside information on diet and lifestyle.
Findings from the iFish study supports current government guidance which recommends the consumption of two portions of fish per week, with two portions of fish per week significantly increasing n-3 PUFA concentrations amongst women of childbearing age independently of FADS genotype.
Conway M.C., McSorley E.M., Mulhern M.S., Spence T., van Wijngaarden E., Watson G.E., Wahlberg K., Pineda D., Broberg K., Hyland B.W., Cobice D.F., Strain J.J., Yeates A.J. (2021) The influence of fish consumption on serum n-3 polyunsaturated fatty acid (PUFA) concentrations in women of childbearing age: a randomised controlled trial (the iFish Study). Eur. J. Nutr. 60(3):1415-1427. DOI: 10.1007/s00394-020-02326-w