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Our current research interests are associated with understanding the interplay between genomics, epigenomics and the environment on healthy development, healthy ageing and in complex/chronic disease manifestation. The overarching aim is to provide scientific substantiation for new healthcare strategies to promote healthy aging and disease prevention.

Harnessing large-scale research efforts from published genome-wide association studies, epigenome-wide association studies, and valuable resources such as the UK Biobank, our research team use bioinformatic approaches to meta-analyse data with that from interdisciplinary projects at Ulster University.  We also work closely with a network of multinational collaborators to analyse data from  powerful randomised control trials, studies of vitamin intake in pregnancy, obesity, exercise, DNA damage and bariatric surgery.

In addition to large -omics approaches, the research team are interested in gene-editing, and using molecular biology-based approaches to further investigate mechanistic processes in cell models and tissues.

Lead Investigator

Dr Rachelle Irwin

School of Biomedical Sciences
Coleraine
Room: W1047
+44 28 7012 4674
r.irwin@ulster.ac.uk
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