Lecturer in Pharmacology and Molecular Pathology

Dr Charlotte Moffett

School of Biomedical Sciences

Coleraine campus

Room W1068 Cromore Road Coleraine Co. Londonderry BT52 1SA

Biomedical Sciences Research

Lecturer in Pharmacology and Molecular Pathology

Dr Charlotte Moffett


Overview

Dr Moffett’s present research is funded by a prestigious 5-year RD Lawrence Fellowship awarded by Diabetes UK which explores how infertility develops in women with obesity-diabetes.

In particular, she is investigating whether using drugs to balance the levels of different gut hormones could help these women to have children in the future.

This research builds on a strong portfolio of recent and ongoing research looking at the role of non-classical islet peptides in beta-cell function and the intra-islet adaptive responses to pregnancy, increased insulin demand and type 2 diabetes.

Such research has explored the relevance of local alpha-cell production of GLP-1 and the modulatory effects of established and new antidiabetic drugs on the process of islet cell transdifferentiation necessary for building beta-cell mass.