School of Biomedical Sciences
Cromore Road,
Coleraine,
Co. Londonderry,
BT52 1SA,
Dr Charlotte Moffett
Overview
Dr Moffett’s present research is funded by a prestigious 5-year RD Lawrence Fellowship awarded by Diabetes UK which explores how infertility develops in women with obesity-diabetes.
In particular, she is investigating whether using drugs to balance the levels of different gut hormones could help these women to have children in the future.
This research builds on a strong portfolio of recent and ongoing research looking at the role of non-classical islet peptides in beta-cell function and the intra-islet adaptive responses to pregnancy, increased insulin demand and type 2 diabetes.
Such research has explored the relevance of local alpha-cell production of GLP-1 and the modulatory effects of established and new antidiabetic drugs on the process of islet cell transdifferentiation necessary for building beta-cell mass.
Research Opportunities
| Title | Closing Date |
|---|---|
| Maternal butyrate in obesity: implication for insulin and glucose metabolism in offspring Funded PhD Opportunity Funded PhD Opportunity | Monday 27 February 2023 4:00PM |
| Gut hormone analogues in the treatment and prevention of endometrial cancer in obese-diabetic females Funded PhD Opportunity Funded PhD Opportunity | Monday 27 February 2023 4:00PM |
| Mechanisms of islet adaptation in pregnancy: impact of estrogen and progesterone on pancreatic β-cell energy metabolism Funded PhD Opportunity Funded PhD Opportunity | Monday 27 February 2023 4:00PM |