School of Biomedical Sciences
Cromore Road,
Coleraine,
Co. Londonderry,
BT52 1SA,
Professor Diane Lees-Murdock
Overview
Research Interests
Investigating epigenetic regulation in normal development and disease e.g. osteoarthritis and hypertension. Particular focus is on the role of DNA methyltransferase enzymes in carrying out faithful transmission of the DNA methylation pattern and their contribution to onset and pathology of disease.
Investigating the influence of environmental factors such as nutrients and xenobiotics on DNA methylation maintenance and reprogramming.
Teaching interests
Diane obtained a Postgraduate Certificate in Higher Education Practice and has been a Fellow of the Higher Education Authority since 2008.
She designed and leads the innovative online Postgraduate Diploma Stem Cell Biology programme which was developed with BBSRC Modular Training for Industry funding. For full details of this course see our prospectus page
Administrative roles
Deputy Chairperson for the Royal Society of Biology, N. Ireland Branch
Chair of the judging panel of the Undergraduate Awards Life Sciences section
Research Opportunities
| Title | Closing Date |
|---|---|
| The Development of 3D engineered glioblastoma tumour models for precision medicine Funded PhD Opportunity Funded PhD Opportunity | Friday 27 February 2026 4:00PM |
| Epigenomic: Mechanisms Underlying Hypertension and GLP-1 RA Efficacy Funded PhD Opportunity Funded PhD Opportunity | Friday 27 February 2026 4:00PM |



