Exploring the Cardiovascular Health Benefits of Novel Marine Lipids

Summary

This MRes project will focus on the development and investigation of the health benefits of sustainable marine derived lipids. In particular, the project will focus on fish oils derived from certain North Atlantic fish which are naturally rich in the long chain mono-unsaturated fatty acids (LCMUFA) cetoleic acid. LCMUFAs have been linked to improvements in several key risk factors associated with metabolic health including reductions in LDL-cholesterol, total cholesterol, glucose levels as well as enhanced insulin sensitivity. Studies also show an improvement in adipocyte health with a reduction in hypertrophy of the cells and increased levels of the anti-inflammatory and insulin regulating hormone adiponectin. This MRes will investigate the effect of a unique blend of more sustainable marine derived lipids on cardiovascular and metabolic health related outcomes.

Objectives of the research:

• Conduct a systematic review on the health benefits of very long chain marine-derived lipids.
• Conduct a human intervention study to assess the efficacy of a novel marine lipid blend for improving indicators of cardiovascular and metabolic health related outcomes.

Methods to be used:

A parallel randomized controlled human intervention study will be conducted in adults (18-65 yrs). Participants will be randomly allocated to one of three intervention groups: (I) Omega-3 supplement group, (ii) Omega 3-9-11 group or (iii) a placebo supplement group. Pre and post intervention analysis will include lifestyle and anthropometric assessment along with the biochemical analysis of human biological samples for markers of cardiovascular health. Statistical analysis of large data sets along with report writing will be integral to its success.

Essential criteria

Applicants should hold, or expect to obtain, a First or Upper Second Class Honours Degree in a subject relevant to the proposed area of study.

We may also consider applications from those who hold equivalent qualifications, for example, a Lower Second Class Honours Degree plus a Master’s Degree with Distinction.

In exceptional circumstances, the University may consider a portfolio of evidence from applicants who have appropriate professional experience which is equivalent to the learning outcomes of an Honours degree in lieu of academic qualifications.

• Sound understanding of subject area as evidenced by a comprehensive research proposal
• A comprehensive and articulate personal statement

Desirable Criteria

If the University receives a large number of applicants for the project, the following desirable criteria may be applied to shortlist applicants for interview.

• First Class Honours (1st) Degree
• Practice-based research experience and/or dissemination
• Experience using research methods or other approaches relevant to the subject domain
• Publications record appropriate to career stage
• Experience of presentation of research findings

Equal Opportunities

The University is an equal opportunities employer and welcomes applicants from all sections of the community, particularly from those with disabilities.

Appointment will be made on merit.

Funding and eligibility

This opportunity is open to all applicants.

The tuition fee for international and EU (excluding ROI) candidates is £19,040 for 2026/27.

Studentship funding is available to UK and ROI applicants, as follows:

• MRes studentships will be available to top ranked candidates to cover tuition fees and a Research Training Support Grant of £900.
• All applicants to the project will be considered automatically for an MRes studentship.
• Applicants who do not receive a studentship but meet admission requirements may be offered admission on a self-funded basis.
• Applicants who already hold an MRes or a doctoral degree or who have been registered on a programme of research leading to the award of an MRes or doctoral degree are NOT eligible to apply for funding.
• Applicants who hold or who are registered on a taught Master’s degree are eligible to apply.