“This Unit of Assessment represents a large and diverse range of disciplines.
Alongside a world-leading (100% 4*) research environment, I am especially proud of our achievements to translate research outcomes into meaningful impact for the benefit of wider society.
This has only been made possible by our talented and dedicated academic, research, technical and business support staff – a true team effort!”
Research Directors
Unit of Assessment Coordinators
Professor Ciara Hughes
Professor of Health Science Research-
Areas of expertise
- Interventions for pain/fatigue reduction along with associated underpinning biomarkers and cellular changes
- Radiation dose reduction along with the associated underpinning biomarkers and cellular changes
People Involved
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Our Team
Name Role Abdel-Wahab, Y Dr Reader Allsopp, P Dr Lecturer in Human Nutrition Anderson, R Professor Professor of Vision Science Atkinson, S Dr Lecturer in Stratified Medicine (Vision) Banat, I Professor Professor of Microbial Biotechnology Barr, O Professor Professor of Nursing and Intellectual Disabilities Beck, ER Dr Lecturer in Nursing Beirne, R Dr Lecturer in Optometry Berggren, PO Professor Professor of Molecular and Cellular Endocrinology Bjourson, A Professor Professor Of Genomics Black, P Dr Lecturer Blackburn, N Dr Lecturer in Healthcare Science Bleakley, C Dr Senior Lecturer Boomer, C Miss Research Fellow - Nursing Research & Practice Development Breen, C Dr Lecturer in Clinical Physiology Breslin, K Dr Lecturer in Optometry Brown, D Dr Senior Lecturer in Nursing Burnett, K Professor Professor of Pharmacy Education Callan, B Dr Senior Lecturer Callan, J Professor The Norbrook Chair in Pharmaceutical Science Casson, K Dr Lecturer In Health Promotion Cathcart, J Dr Senior Lecturer Coates, V Professor Professor of Nursing Practice Research Cobice, D Dr Lecturer in Bioanalytical Chemistry Coleman, H Dr Lecturer in Pharmaceutical Chemistry Conway, C Dr Scientific Assistant Cook, N Professor Associate Head of School of Nursing Courtenay, A Dr Lecturer in Clinical Pharmacy Cundell, J Dr Lecturer Practitioner in Podiatry Curran, C Professor Executive Dean Dolk, H Professor Professor of Epidemiology & Health Services Research Dooley, J Professor Professor of Microbiology Dornan, L Dr Lecturer in Nursing Douglas, P Mrs Senior Lecturer/Clinical Dietetics Facilitator Duddy, W Dr Lecturer in Stratified Medicine (Bioinformatics) Duguez, S Dr Senior Lecturer Flatt, P Professor Research Director- Biomedical Sciences Gallagher, A Professor Head of the Doctoral College (Coleraine/Magee) Gault, V Professor Associate Dean (Research and Impact) Gibson, D Dr Senior Lecturer Gill, C Dr Senior Lecturer Gillen, P Dr Reader in Nursing and Midwifery Research and Development Given, J Dr Research Fellow - EUROlinkCAT Gracey, J Dr Lecturer Hannon-Fletcher, M Dr Professor of Biomedical Science Hasson, F Dr Senior Lecturer Hawthorne, S Dr Lecturer in Pharmaceutical Biosciences Hill, A Dr Senior Lecturer Hoey, L Dr Lecturer in Human Nutrition Hughes, C Dr Lecturer in Public Health Nutrition Hughes, C Professor Associate Research Director - School of Nursing and School of Health Sciences Irwin, N Professor Professor Irwin, R Dr Lecturer in Genomic Medicine Jack, I Mr Lecturer in Clinical Pharmacy Kelly, C Dr Senior Lecturer Kernohan, G Professor Professor of Health Research Kerr, D Professor Head of School of Health Sciences Kerr, M Dr Lecturer in Food Regulatory Affairs Lagan, B Dr Lecturer In Nursing Laird, E Dr Lecturer In Nursing Lees-Murdock, D Dr Senior Lecturer Liddle, D Dr Lecturer in Health & Rehabilitation Sciences Little, JA Dr Associate Research Director - School of Biomedical Sciences Loane, M Dr Senior Research Fellow Logue, C Dr Lecturer in Dietetics Lowry, D Dr Lecturer in Pharamceutical Sciences Magee, P Dr Senior Lecturer in Human Nutrition Marley, J Dr Lecturer in Physiotherapy (Musculoskeletal) Martin, S Professor Professor of Occupational Therapy Matchett, K Dr Lecturer in Molecular Immunology McAloon, T Dr Lecturer in Nursing McAnena, L Dr Regulatory Research Officer McCance, T Professor The Mona Grey Professor of Nursing Research & Development McCann, M Dr Faculty Partnership Manager (Life & Health Sciences) McCarron, P Professor Head of School of Pharmacy and Pharmaceutical Sciences McCaughan, E Professor Professor of Cancer Care McCauley, C Dr Lecturer in Health Sciences McClean, P Dr Senior Lecturer McClean, S Professor Head of School of Biomedical Sciences McClelland, J Dr Senior Lecturer McConnell, D Dr Lecturer in Nursing McCullough, S Dr Lecturer in Optometry McDonough, S Professor Professor of Health and Rehabilitation McDowell, A Dr Lecturer in Molecular Microbiology McFadden, S Dr Senior Lecturer McGarvey, H Dr Senior Lecturer McGilligan, V Dr Senior Lecturer McHale, A Professor Professor of Medical Biotechnology McIlfatrick, S Professor Head of School and Professor of Nursing and Palliative Care McKenna, D Dr Associate Head of School of Biomedical Sciences McKenna, H Professor Professor Nursing McKillop, A Professor Associate Dean (Education) McNulty, H Professor Professor of Nutritional Science McSorley, E Dr Senior Lecturer in Human Nutrition Melby, V Dr Senior Lecturer Mitchell, C Professor Professor of Tissue Regeneration Moffett, C Dr Lecturer in Pharmacology and Molecular Pathology Moore, K Dr Lecturer in Nursing Moore, T Professor Professor of Personalised Medicine Moorhead, A Dr Senior Lecturer Moran, F Dr Lecturer Mulhern, M Dr Lecturer in Food Science Mulholland, P Dr Lecturer in Optometry Murray, E Dr Lecturer in Stratified Medicine (Mental Health) Naughton, P Dr Senior Lecturer in Medical Microbiology Naughton, V Dr Senior Lecturer Nesbit, A Dr Senior Lecturer in Molecular Biology O'Hagan, B Dr Lecturer in Pathobiology O'Harte, F Professor Professor of Endocrinology & Metabolism O'Neill, B Dr Senior Lecturer Parahoo, K Professor Research Director - Institute of Nursing and Health Research Pedlow, K Dr Lecturer in Physiotherapy Pentieva, K Professor Professor of Human Nutrition Porter-Armstrong, A Dr Senior Lecturer in Rehabilitation Sciences Pourshahidi, K Dr Lecturer in Food Science and Technology Price, R Dr Clinical Trials Manager Quinn, V Miss Scientific Assistant (C-Tric) Rai, TS Dr Lecturer in Cellular Ageing Ray, S Professor Professor of Global Nutrition (Health and Disease) Reid, B Dr Lecturer in Nursing Richardson, P Mr Lecturer Optometry Clinic Manager Rorsman, P Professor Professor of Cellular and Experimental Diabetes Ryan, A Professor Professor of Ageing and Health Saunders, K Professor Professor of Optometry and Vision Science Semple, C Dr Reader in Clinical Nursing Shukla, P Dr Lecturer in Stratified Medicine (Bioinformatics) Sinclair, M Professor Professor of Midwifery Research Singh - Nee Nigam, P Dr Senior Lecturer in Biotechnology Sittlington, J Dr Scientific Assistant Slater, P Dr Senior Lecturer in Statistics Snelling, W Dr Research Associate Stinson, M Dr Lecturer Strain, S Professor Professor of Human Nutrition Taggart, L Dr Professor of Intellectual Disability Research Tambuwala, M Dr Lecturer in Pharmacy Tarasov, A Dr Senior Lecturer in Cellular and Experimental Diabetes Ternan, N Dr Senior Lecturer Thomas, K Mr Scientific Assistant Thompson, P Dr Senior Lecturer Titterington, J Dr Lecturer in Speech & Language Therapy (Paediatrics) Tully, M Professor Professor of Public Health Walsh, C Professor Professor of Genetics Ward, M Professor Professor of Nutrition and Dietetics Watterson, S Dr Lecturer in Computational Biology (Hypertension) Webba Da Silva, M Dr Reader of Pharmaceutical Chemistry White, B Mrs Lecturer in Clinical & Pharmacy Practice Willoughby, C Professor Professor of Ophthalmology Xu, G Professor Professor of Epigenetics Yeates, A Dr Lecturer In Biomedical Sciences Zhang, SD Dr Senior Lecturer
“We are delighted with these REF results which confirm our ranking as one of the leading Centres of international excellence for research in the UK for Allied Health Professions. These outstanding results are testimony to the sustained vitality of Ulster’s world class research and builds significantly on the notable successes already achieved in REF2014, including a 32% growth in the number of outstanding researchers.”
Impact Case Studies and Environment Statement
Research Outputs
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View the outputs
- 5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels.
- 5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Transcriptome Reprogramming during Differentiation
- A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin
- A descriptive systematic review of salivary therapeutic drug monitoring in neonates and infants
- A gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mapping
- A long-acting, dual-agonist analogue of lamprey GLP-1 shows potent insulinotropic, β-cell protective, and anorexic activities and improves glucose homeostasis in high fat-fed mice
- A loyalty scheme to encourage physical activity in office workers: a cluster RCT
- A mixed-methods, randomized controlled feasibility trial of Eye Movement Desensitization and Reprocessing (EMDR) plus Standard Care (SC) versus SC alone for DSM-5 Posttraumatic Stress Disorder (PTSD) in adults with intellectual disabilities
- A new stable GIP-Oxyntomodulin hybrid peptide improved bone strength both at the organ and tissue levels in genetically-inherited type 2 diabetes mellitus
- A non-linear time-series analysis approach to identify thresholds in associations between population antibiotic use and rates of resistance
- A Novel CCK-8/GLP-1 Hybrid Peptide Exhibiting Prominent Insulinotropic, Glucose-Lowering, and Satiety Actions With Significant Therapeutic Potential in High-Fat-Fed Mice
- A novel DPP IV-resistant C-terminally extended glucagon analogue exhibits weight-lowering and diabetes-protective effects in high-fat-fed mice mediated through glucagon and GLP-1 receptor activation
- A novel genomic signature reclassifies an oral cancer subtype
- A novel role for CRIM1 in the corneal response to UV and pterygium development
- A novel urinary biomarker approach reveals widespread exposure to multiple low-calorie sweeteners in adults : LCS exposure in adults via a biomarker approach
- A qualitative study exploring midwives’ perceptions and knowledge of maternal obesity : Reflecting on their experiences of providing healthy eating and weight management advice to pregnant women
- A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57
- A rapid and sensitive system for recovery of nucleic acids from Mycobacteria sp. on archived glass slides
- A realist process evaluation within the Facilitating Implementation of Research Evidence (FIRE) cluster randomised controlled international trial: an exemplar
- A systematic review of the application and psychometric properties of the graded Wolf Motor Function Test
- A systematic review of the methodological and practical challenges of undertaking randomised-controlled trials with cognitive disability populations
- A versatile, stimulus-responsive nanoparticle-based platform for use in both sonodynamic and photodynamic cancer therapy
- A vitamin-C-derived DNA modification catalysed by an algal TET homologue
- Accelerometer-measured sedentary and physical activity time and their correlates in European older adults: The SITLESS study
- Acceptability of online exercise-based interventions after breast cancer surgery: systematic review and narrative synthesis
- Access to health care for older people with intellectual disability : a modelling study to explore the cost-effectiveness of health checks
- Accumulated brisk walking reduces arterial stiffness in overweight adults: Evidence from a randomized control trial
- Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote
- Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties
- Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype–phenotype correlations, codon bias and dominant-negative effects
- Adipsin Is an Adipokine that Improves β Cell Function in Diabetes
- Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells
- Age-Associated Methylation Suppresses SPRY1, Leading to a Failure of Re-quiescence and Loss of the Reserve Stem Cell Pool in Elderly Muscle
- Albumin Nano-Encapsulation of Piceatannol Enhances Its Anticancer Potential in Colon Cancer Via Downregulation of Nuclear p65 and HIF-1 alpha
- Alzheimer's disease–like pathology has transient effects on the brain and blood metabolome
- An enzymatically stable GIP/xenin hybrid peptide restores GIP sensitivity, enhances beta cell function and improves glucose homeostasis in high-fat-fed mice
- An integrated meta-analysis approach to identifying medications with potential to alter breast cancer risk through connectivity mapping
- An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway
- An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity
- An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
- An ultrasound responsive microbubble-liposome conjugate for targeted irinotecan-oxaliplatin treatment of pancreatic cancer
- An universally calibrated microplate ferric reducing antioxidant power (FRAP) assay for foods and applications to Manuka honey
- Antidiabetic drug therapy alleviates type 1 diabetes in mice by promoting pancreatic α-cell transdifferentiation
- Antimicrobial consumption and resistance in adult hospital inpatients in 53 countries: results of an internet-based global point prevalence survey
- Antisense PMO cocktails effectively skip dystrophin exons 45-55 in myotubes transdifferentiated from DMD patient fibroblasts
- Antisepsis of the skin before spinal surgery with povidone iodine-alcohol followed by chlorhexidine gluconate-alcohol versus povidone iodine-alcohol applied twice for the prevention of contamination of the wound by bacteria
- Appetite-regulating hormones-leptin, adiponectin and ghrelin-and the development of prostate cancer: a systematic review and exploratory meta-analysis.
- Application of Liquid Chromatography−Tandem Mass Spectrometry To Determine Urinary Concentrations of Five Commonly Used Low-Calorie Sweeteners: A Novel Biomarker Approach for Assessing Recent Intakes?
- Application of objective physical activity measurement in an antenatal physical activity consultation intervention : a randomised controlled trial
- Assessing computerized eye tracking technology for gaining insight into expert interpretation of the 12-lead electrocardiogram : an objective quantitative approach
- Assessing the availability of the teratogenic drug isotretinoin outside the pregnancy prevention programme: a survey of e-pharmacies
- Association of Genetic Variation with Keratoconus
- Associations of blood mercury and fatty acid concentrations with blood mitochondrial DNA copy number in the Seychelles Child Development Nutrition Study
- Automated Pupillometry Using a Prototype Binocular Optical Coherence Tomography System
- Axial growth and refractive change in white European children and young adults: predictive factors for myopia
- Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
- Behavior change theory, content and delivery of interventions to enhance adherence in chronic respiratory disease: A systematic review
- Behavioural incentive interventions for health behaviour change in young people (5-18 years old): A systematic review and meta-analysis
- Beneficial actions of a long-acting apelin analogue in diabetes are related to positive effects on islet cell turnover and transdifferentiation
- Beneficial effects of a N-terminally modified GIP agonist on tissue-level bone material properties
- Beneficial long-term antidiabetic actions of N- and C-terminally modified analogues of apelin-13 in diet-induced obese diabetic mice
- Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice
- Beta-blocker use in pregnancy and risk of specific congenital anomalies: : A European case-malformed control study
- Biological Activity and Antidiabetic Potential of C-Terminal Octapeptide Fragments of the Gut-Derived Hormone Xenin
- Biological markers as an outcome measure of exercise in cancer rehabilitation: A systematic review
- Biotransformation of Silver Released from Nanoparticle Coated Titanium Implants Revealed in Regenerating Bone
- BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
- Breakfast Consumption in the UK: Patterns, Nutrient Intake and Diet Quality. : A Study from the International Breakfast Research Initiative Group
- Breastfeeding, Motivation and Culture: an exploration of maternal influences within midwife-led instruction in an Asian setting
- B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study
- B-vitamin status in relation to bone mineral density in treated celiac disease patients
- B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age : The Trinity Ulster Department of Agriculture (TUDA) Cohort Study
- CandiMeth: Powerful yet simple visualization and quantification of DNA methylation at candidate genes
- Carbon quantum dot-NO photoreleaser nanohybrids for two-photon phototherapy of hypoxic tumors
- Cathepsin B-degradable, NIR-responsive nanoparticulate platform for target-specific cancer therapy
- CD133 in brain tumor: the prognostic factor
- Changes in Physical Activity and Sedentary Behavior in Response to COVID-19 and Their Associations with Mental Health in 3052 US Adults
- Changes in physical activity predict changes in a comprehensive model of balance in older community-dwelling adults. A longitudinal analysis of the TILDA study
- Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment
- Children Navigating Parental Cancer: Outcomes of a Psychosocial Intervention
- Cinacalcet corrects hypercalcemia in mice with an inactivating Gα11 mutation
- Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis
- Co-delivery of a RanGTP inhibitory peptide and doxorubicin using dual loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer cells
- Color discrimination in individuals with light and dark irides: an evaluation of the effects of intraocular straylight and retinal illumination
- Combined sonodynamic and antimetabolite therapy for the improved treatment of pancreatic cancer using oxygen loaded microbubbles as a delivery vehicle
- Communication Skills Training for Practitioners to Increase Patient Adherence to Home-Based Rehabilitation for Chronic Low Back Pain: Results of a Cluster Randomized Controlled Trial
- Comparative Genomics of Carriage and Disease Isolates of Streptococcus pneumoniae Serotype 22F Reveals Lineage-Specific Divergence and Niche Adaptation
- Comparing patient generated blood glucose diary records with meter memory in type 2 diabetes
- Comparison of the independent and combined effects of sub-chronic therapy with metformin and a stable GLP-1 receptor agonist on cognitive function, hippocampal synaptic plasticity and metabolic control in high-fat fed mice
- Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis
- Consequences of Physical Inactivity in Older Adults: A Systematic Review of Reviews and Meta-Analyses
- Consumption of a soy drink has no effect on cognitive function but may alleviate vasomotor symptoms in post-menopausal women; a randomised trial
- Control of Klebsiella pneumoniae Infection in Mice by Using Dissolving Microarray Patches Containing Gentamicin
- Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex
- Correction of the Exon 2 Duplication in DMD Myoblasts by a Single CRISPR/Cas9 System
- Correlates of symptoms of anxiety and depression and mental wellbeing associated with COVID-19: a cross-sectional study of UK-based respondents
- Correlation between low FAT1 expression and early affected muscle in facioscapulohumeral muscular dystrophy
- CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting
- CRISPR/Cas9 gene editing demonstrates metabolic importance of GPR55 in the modulation of GIP release and pancreatic beta cell function
- Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
- Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
- Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance
- Depletion of DNMT1 in differentiated human cells highlights key classes of sensitive genes and an interplay with polycomb repression
- Developing a best practice model for partnership practice between specialist palliative care and intellectual disability services: A mixed methods study
- Development and characterisation of novel, enzymatically stable oxytocin analogues with beneficial antidiabetic effects in high fat fed mice
- Diabetes in people with intellectual disabilities: A systematic review of the literature
- Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity
- Direct Evidence of Multi-Bubble Sonoluminescence using Therapeutic Ultrasound and Microbubbles
- DNA methylation of hypertension-related genes and effect of riboflavin supplementation in adults stratified by genotype for the MTHFR C677T polymorphism
- Dogfish glucagon analogues counter hyperglycaemia and enhance both insulin secretion and action in diet-induced obese diabetic mice
- Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production
- Economic implications of reducing caesarean section rates – Analysis of two health systems
- Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring trial)
- Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Corneal Epithelium Using a Modified Cell Penetrating Peptide
- Effectiveness of advance care planning with family carers in dementia nursing homes: A paired cluster randomized controlled trial
- Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (the REVIVE trial)
- Effects of long-acting GIP, xenin and oxyntomodulin peptide analogues on alpha-cell transdifferentiation in insulin-deficient diabetic GluCreERT2;ROSA26-eYFP mice
- Efficient Translation of Dnmt1 Requires Cytoplasmic Polyadenylation and Musashi Binding Elements
- Electroneutral polymersomes for combined cancer chemotherapy
- Elevated Melatonin Levels Found in Young Myopic Adults Are Not Attributable to a Shift in Circadian Phase
- Encoding canonical DNA quadruplex structure
- Endocannabinoids, endocannabinoid-like molecules and their precursors in human small intestinal lumen and plasma: does diet affect them?
- Enhanced expression of beta cell Ca(v)3.1 channels impairs insulin release and glucose homeostasis
- Enzymatically stable analogue of the gut-derived peptide xenin on beta-cell transdifferentiation in high fat fed and insulin-deficient Ins1Cre/+;Rosa26-eYFP mice
- Epidemiology of multiple congenital anomalies in Europe: a EUROCAT population-based registry study
- Erythropoietin drives breast cancer progression by activation of its receptor EPOR
- Esculentin-2CHa(1–30) and its analogues: stability and mechanisms of insulinotropic action
- EUROmediCAT signal detection: an evaluation of selected congenital anomaly-medication associations
- Evaluating a psychosocial intervention for men with prostate cancer and their partners: Outcomes and lessons learned from a randomized controlled trial
- Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells
- Evidence for inhibitory autocrine effects of proinsulin C-peptide on pancreatic β-cell function and insulin secretion
- Evidence from a Randomized Trial That Exposure to Supplemental Folic Acid at Recommended Levels during Pregnancy Does Not Lead to Increased Unmetabolized Folic Acid Concentrations in Maternal or Cord Blood
- Exercise and inflammation in coronary artery disease: A systematic review and meta-analysis of randomised trials
- Exercise rehabilitation following intensive care unit discharge for recovery from critical illness
- Exploring person-centredness in emergency departments: A literature review
- Exploring psychological safety as a component of facilitation within the Promoting Action on Research Implementation in Health Services framework
- Exploring temporal behaviour of app users completing ecological momentary assessments using mental health scales and mood logs
- Eye Tracking the Visual Attention of Nurses Interpreting Simulated Vital Signs Scenarios: Mining Metrics to Discriminate Between Performance Level
- Facilitating Implementation of Research Evidence (FIRE): an international cluster randomised controlled trial to evaluate two models of facilitation informed by the Promoting Action on Research Implementation in Health Services (PARIHS) framework
- Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
- Folic Acid Supplementation in Postpolypectomy Patients in a Randomized Controlled Trial Increases Tissue Folate Concentrations and Reduces Aberrant DNA Biomarkers in Colonic Tissues Adjacent to the Former Polyp Site
- Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes
- Gaming for Health: Systematic Review and Meta-analysis of the Physical and Cognitive Effects of Active Computer Gaming in Older Adults
- Gastrointestinal modifications and bioavailability of brown seaweed phlorotannins and effects on inflammatory markers
- Gastroschisis in Europe – a case-malformed control study of medication and maternal illness during pregnancy as risk factors
- Gemcitabine loaded microbubbles for targeted chemo-sonodynamic therapy of pancreatic cancer
- Gene-specific DNA methylation in newborns in response to folic acid supplementation during the second and third trimesters of pregnancy : epigenetic analysis from a randomized controlled trial
- GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
- Glucagon-like peptides-1 from phylogenetically ancient fish show potent anti-diabetic activities by acting as dual GLP1R and GCGR agonists
- Glucagon-related peptides from phylogenetically ancient fish reveal new approaches to the development of dual GCGR and GLP1R agonists for type 2 diabetes therapy
- Greater yogurt consumption is associated with increased bone mineral density and physical function in older adults
- Gα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy
- Hazardous events in membrane bioreactors – Part 3: Impacts on microorganism log removal efficiencies
- Health care professionals’ perspectives of advance care planning for people with dementia living in long-term care settings: A narrative review of the literature
- Hepatocyte Nuclear Factor 4-Alpha Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver
- Herbal medicinal products or preparations for neuropathic pain
- Highly degradable porous melt-derived bioactive glass foam scaffolds for bone regeneration
- Hip Joint Pathology as a Leading Cause of Groin Pain in the Sporting Population: A 6-Year Review of 894 Cases.
- HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia
- Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity
- Hydrogel-forming microneedles enhance transdermal delivery of metformin hydrochloride
- Hydrogel-Forming Microneedles Prepared from "Super Swelling'' Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery
- Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling
- Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells
- Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium
- Identifying Priorities for Physiotherapy Research in the UK: the James Lind Alliance Physiotherapy Priority Setting Partnership
- Impact of a (poly)phenol-rich extract from the brown algae Ascophyllum nodosum on DNA damage and antioxidant activity in an overweight or obese population: a randomized controlled trial
- Impact of the common MTHFR 677C→T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project
- Impact of the COVID-19 pandemic on radiography practice: findings from a UK radiography workforce survey
- Impact of the MTHFR C677T polymorphism on one-carbon metabolites: Evidence from a randomised trial of riboflavin supplementation
- Impact of voluntary fortification and supplement use on dietary intakes and biomarker status of folate and vitamin B-12 in Irish adults
- Implementing and Measuring Person-centredness using an APP for Knowledge Transfer: the iMPAKT App
- In Silico Screening Based on Predictive Algorithms as a Design Tool for Exon Skipping Oligonucleotides in Duchenne Muscular Dystrophy
- Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity
- Incretin Receptor Null Mice Reveal Key Role of GLP-1 but Not GIP in Pancreatic Beta Cell Adaptation to Pregnancy
- Informal caregiving and mental ill health – differential relationships by workload, gender, age and area-remoteness in a UK region
- In-school eyecare in special education settings has measurable benefits for children’s vision and behaviour : The measurable benefits of in-school eyecare in special education
- Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion
- Intermittent hypoxia in obstructive sleep apnoea mediates insulin resistance through adipose tissue inflammation
- International palliative care research priorities: A systematic review
- Interventions for preventing and treating low-back and pelvic pain during pregnancy
- Interventions for prevention of bullying in the workplace (Review)
- Interventions promoting active transport to school in children: A systematic review and meta-analysis
- Interventions targeting working memory in 4-11 year olds within their everyday contexts: a systematic review
- Intracellular Guest Exchange between Dynamic Supramolecular Hosts
- Investigating the performance of a novel pH and cathepsin B sensitive, stimulus-responsive nanoparticle for optimised sonodynamic therapy in prostate cancer
- In-vivo anterior segment OCT imaging provides unique insight into cerulean blue-dot opacities and cataracts in Down syndrome
- Islet distribution of Peptide YY and its regulatory role in primary mouse islets and immortalised rodent and human beta-cell function and survival
- ‘Keeping my mind strong’: enabling children to discuss and explore issues relating to their perceptions of positive mental health through the arts
- Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy
- Keratinocyte Growth-Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury
- KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies
- Laser-patterned Composite Carbon Structures for Wound Monitoring Technologies
- Liraglutide and sitagliptin counter beta- to alpha-cell transdifferentiation in diabetes
- Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease
- Long term trends in prevalence of neural tube defects in Europe: population based study
- Longitudinal time-lapse in vivo micro-CT reveals differential patterns of peri-implant bone changes after subclinical bacterial infection in a rat model
- Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice
- Major congenital anomalies in babies born with Down syndrome: a EUROCAT population-based registry study
- “Man in the driving seat” : A grounded theory study of the psychosocial experiences of Black African and Black Caribbean men treated for prostate cancer and their partners
- Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability
- Maternal immune markers during pregnancy and child neurodevelopmental outcomes at age 20 months in the Seychelles Child Development Study
- Maternal polymorphisms in glutathione-related genes are associated with maternal mercury concentrations and early child neurodevelopment in a population with a fish-rich diet
- Maternal vitamin D and markers of glycaemia during pregnancy in the Belfast centre of the Hyperglycaemia and Adverse Pregnancy Outcome study
- Maternal Vitamin D Status and the Relationship with Neonatal Anthropometric and Childhood Neurodevelopmental Outcomes: Results from the Seychelles Child Development Nutrition Study
- Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice
- Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study
- Methyl mercury exposure and neurodevelopmental outcomes in the Seychelles Child Development Study Main cohort at age 22 and 24years
- Methylome profiling of young adults with depression supports a link with immune response and psoriasis
- Microfluidic-controlled manufacture of liposomes for the solubilisation of a poorly water soluble drug
- Microneedle-Mediated Transdermal Delivery of Bevacizumab
- Microscopic Investigation of the Combined Use of Antibiotics and Biosurfactants on Methicillin Resistant Staphylococcus aureus
- miR‐210 is induced by hypoxia and regulates neural cell adhesion molecule in prostate cells
- Mll1 is essential for the senescenceassociated secretory phenotype
- Mucoactive agents for acute respiratory failure in the critically ill: a systematic review and meta-analysis
- Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression
- Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia
- Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy
- Mutation-independent Allele-Specific Editing by CRISPR-Cas9, a Novel Approach to Treat Autosomal Dominant Disease
- Myopes have significantly higher serum melatonin concentrations than non-myopes
- Natural quorum sensing inhibitors effectively downregulate gene expression of Pseudomonas aeruginosa virulence factors
- Neural bandwidth of veridical perception across the visual field
- Nontargeted LC-MSn Profiling of Compounds in Ileal Fluids That Decrease after Raspberry Intake Identifies Consistent Alterations in Bile Acid Composition
- Novel dual incretin agonist peptide with antidiabetic and neuroprotective potential
- Nursing students’ attitudes towards obese people, knowledge of obesity risk, and self-disclosure of own health behaviours : an exploratory survey
- Nutrition Education and Community Pharmacy: A First Exploration of Current Attitudes and Practices in Northern Ireland
- Online support groups for women with breast cancer (Review)
- Ontogeny, conservation and functional significance of maternally inherited DNA methylation at two classes of non-imprinted genes
- OptiBIRTH: A cluster randomised trial of a complex intervention to increase vaginal birth after caesarean section
- Optimising the glaucoma signal/noise ratio by mapping changes in spatial summation with area-modulated perimetric stimuli
- Oxygen carrying microbubbles for enhanced sonodynamic therapy of hypoxic tumours
- Oxygen generating nanoparticles for improved photodynamic therapy of hypoxic tumours
- Paediatric International Nursing Study: using person-centred key performance indicators to benchmark children’s services
- Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point
- Patient and service-related barriers and facitators to the acceptance and use of interventions to promote communication in health and social care: a realist review
- Patients’ experiences of in-hospital care when nursing staff were engaged in a practice development programme to promote person-centredness: A narrative analysis study
- Peptide YY (1–36) peptides from phylogenetically ancient fish targeting mammalian neuropeptide Y1 receptors demonstrate potent effects on pancreatic β-cell function, growth and survival
- Perceived caring attributes and priorities of pre-registration nursing students throughout a nursing curriculum underpinned by person-centredness
- Pharmacological characterization and antidiabetic activity of a long-acting glucagon-like peptide-1 analogue conjugated to an antithrombin III-binding pentasaccharide
- Pharmacological potential of novel agonists for FFAR4 on islet and enteroendocrine cell function and glucose homeostasis
- Physical rehabilitation interventions for adult patients during critical illness: an overview of systematic reviews
- Polymorphisms in ATP-binding cassette transporters associated with maternal methylmercury disposition and infant neurodevelopment in mother-infant pairs in the Seychelles Child Development Study
- Polyunsaturated fatty acid status and methylmercury exposure are not associated with leukocyte telomere length in mothers or their children in the Seychelles Child Development Study
- Porphyrin Production and Regulation in Cutaneous Propionibacteria
- Possible role of diet in cancer: systematic review and multiple meta-analyses of dietary patterns, lifestyle factors, and cancer risk
- Prenatal exposure to methyl mercury from fish consumption and polyunsaturated fatty acids: associations with child development at 20 mo of age in an observational study in the Republic of Seychelles
- Prenatal methylmercury exposure and DNA methylation in seven-year-old children in the Seychelles Child Development Study
- Prescribing of Antidiabetic Medicines before, during and after Pregnancy: A Study in Seven European Regions
- Prescription of antiepileptic medicines including valproate in pregnant women: A study in three European countries
- Prevalence and clinical profile of microcephaly in South America pre-Zika, 2005-14: prevalence and case-control study
- Prevalence and risk of Down syndrome in monozygotic and dizygotic multiple pregnancies in Europe : implications for prenatal screening
- Profile of refractive errors in European Caucasian children with Autistic Spectrum Disorder; increased prevalence and magnitude of astigmatism
- Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 mice
- Propionibacterium avidum: a virulent pathogen causing hip periprosthetic joint infection
- Proteomic profile of cystic fibrosis sputum cells in adults chronically infected with Pseudomonas aeruginosa
- Public attitudes to the rights and community inclusion of people with intellectual disabilities: A transnational study
- Quality of life in men living with advanced and localised prostate cancer in the UK : a population-based study
- Quantification of 11β-hydroxysteroid dehydrogenase 1 kinetics and pharmacodynamic effects of inhibitors in brain using mass spectrometry imaging and stable-isotope tracers in mice
- Quantitative antisense screening and optimization for exon 51 skipping in Duchenne muscular dystrophy
- Ran GTPase promotes cancer progression via Met receptor-mediated downstream signaling
- Randomised controlled trial of a tailored information pack for patients undergoing surgery and treatment for rectal cancer
- Recovery From a First-Time Lateral Ankle Sprain and the Predictors of Chronic Ankle Instability: A Prospective Cohort Analysis
- Relationships between seafood consumption during pregnancy and childhood and neurocognitive development: Two systematic reviews
- Repair of the TGFBI gene in human corneal keratocytes derived from a granular corneal dystrophy patient via CRISPR/Cas9-induced homology-directed repair
- Resistance to HSP90 inhibition involving loss of MCL1 addiction
- Resolution acuity across the visual field for mesopic and scotopic illumination
- Response to interferons and antibacterial innate immunity in the absence of tyrosine-phosphorylated STAT1
- Responses of GLP1-secreting L-cells to cytotoxicity resemble pancreatic β-cells but not α-cells
- REST is a hypoxia-responsive transcriptional repressor
- Reversible changes in pancreatic islet structure and function produced by elevated blood glucose
- Riboflavin supplementation alters global and gene-specific DNA methylation in adults with the MTHFR 677 TT genotype
- Risk Factors for Congenital Heart Disease: the Baby Hearts Study, a population-based case-control study
- RISUS study: Rugby Injury Surveillance in Ulster Schools
- Role of Endogenous GLP-1 and GIP in Beta Cell Compensatory Responses to Insulin Resistance and Cellular Stress
- Rose Bengal-Amphiphilic Peptide Conjugate for Enhanced Photodynamic Therapy of Malignant Melanoma
- Seated buttocks anatomy and its impact on biomechanical risk
- Selective Serotonin Reuptake Inhibitor (SSRI) Antidepressants in Pregnancy and Congenital Anomalies: Analysis of linked databases in Wales, Norway and Funen, Denmark
- Selective serotonin reuptake inhibitor antidepressant use in first trimester pregnancy and risk of specific congenital anomalies: A European register-based study
- Selective serotonin reuptake inhibitor prescribing before, during and after pregnancy : a population‐based study in six European regions
- Self-efficacy and self-care behaviours among adults with type 2 diabetes
- Self-reported visual difficulties in Europe and related factors: a European population-based cross-sectional survey
- Sentrin/SUMO Specific Proteases as Novel Tissue-Selective Modulators of Vitamin D Receptor-Mediated Signaling
- Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice
- Short-term CFTR inhibition reduces islet area in C57BL/6 mice
- siRNA Silencing of the Mutant Keratin 12 Allele in Corneal Limbal Epithelial Cells Grown from Patients with Meesmann’s Epithelial Corneal Dystrophy
- Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline
- Six Year Refractive Change among White Children and Young Adults: Evidence for Significant Increase in Myopia among White UK Children
- Skeletal muscle characteristics are preserved in hTERT/cdk4 human myogenic cell lines
- Spatial Localization and Quantitation of Androgens in Mouse Testis by Mass Spectrometry Imaging
- Spatial Localization of Vitamin D Metabolites in Mouse Kidney by Mass Spectrometry Imaging
- Spatiotemporal Summation of Perimetric Stimuli in Early Glaucoma
- Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1
- Structural basis for delta cell paracrine regulation in pancreatic islets
- Suboptimal Biochemical Riboflavin Status Is Associated with Lower Hemoglobin and Higher Rates of Anemia in a Sample of Canadian and Malaysian Women of Reproductive Age
- Supervised walking in comparison with fitness training for chronic back pain in physiotherapy: results of the SWIFT single-blinded randomized controlled trial (ISRCTN17592092).
- Supplementation with calcium and short-chain fructo-oligosaccharides affects markers of bone turnover but not bone mineral density in postmenopausal women
- Supramolecular nanoreactors for intracellular singlet-oxygen sensitization
- Surface-Adsorbed Long G-Quadruplex Nanowires Formed by G:C Linkages
- Survival motor neuron protein deficiency impairs myotube formation by altering myogenic gene expression and focal adhesion dynamics
- Sustained high-fat diet modulates inflammation, insulin signalling and cognition in mice and a modified xenin peptide ameliorates neuropathology in a chronic high-fat model
- Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells
- Synthesis and Evaluation of a Series of Long-Acting Glucagon-Like Peptide-1 (GLP-1) Pentasaccharide Conjugates for the Treatment of Type 2 Diabetes
- Targeted delivery of the hydroxylase inhibitor DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis
- Targeting Hypoxic Prostate Tumors Using the Novel Hypoxia-Activated Prodrug OCT1002 Inhibits Expression of Genes Associated with Malignant Progression
- Testing a diabetes keotacidosis simulation in critical care nursing: A randomized control trial
- Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming
- TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling
- The association between balance and free-living physical activity in an older community-dwelling adult population: a systematic review and meta-analysis
- The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis
- The challenges and psychological impact of delivering nursing care within a war zone
- The Changing Profile of Astigmatism in Childhood: The NICER Study
- The clonal relationships between pre‐cancer and cancer revealed by ultra‐deep sequencing
- The Effect of Short-term Foot Reflexology in Improving Constipation Symptoms During Pregnancy: A Two-armed, Randomized Controlled Trial
- The effectiveness and complexity of interventions targeting sedentary behaviour across the lifespan: a systematic review and meta-analysis
- The effectiveness of interventions aimed at increasing physical activity in adults with persistent musculoskeletal pain: a systematic review and meta-analysis
- The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with haptocorrin glycosylation
- The influence of fish consumption on serum n-3 polyunsaturated fatty acid (PUFA) concentrations in women of childbearing age - a randomised controlled trial (the iFish study)
- The integration of triggered drug delivery with real time quantification using FRET; creating a super ‘smart’ drug delivery system
- The methionine aminopeptidase 2 inhibitor, TNP-470, enhances the antidiabetic properties of sitagliptin in mice by upregulating xenin
- The Physiological and Biochemical Outcomes Associated with a Reflexology Treatment: A Systematic Review
- The prognostic significance of Cdc6 and Cdt1 in breast cancer
- The relationship between adiposity and cognitive function in a large community-dwelling population: data from the Trinity Ulster Department of Agriculture (TUDA) ageing cohort study
- The reliability of the graded Wolf Motor Function Test for stroke
- The rise and fall of pneumococcal serotypes carried in the PCV era
- Tibetan PHD2, an allele with loss-of-function properties
- Topical siRNA delivery to the cornea and anterior eye by hybrid silicon-lipid nanoparticles
- Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders
- Transdermal delivery of gentamicin using dissolving microneedle arrays for potential treatment of neonatal sepsis
- Trends in congenital anomalies in Europe from 1980 to 2012
- Trying to see, failing to focus : near visual impairment in Down syndrome
- Twice daily oral administration of Palmaria palmata protein hydrolysate reduces food intake in streptozotocin induced diabetic mice, improving glycaemic control and lipid profiles
- Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells
- Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex
- Ultrasound‐responsive gene‐activated matrices for osteogenic gene therapy using matrix‐assisted sonoporation
- Urinary, bowel and sexual health in older men from Northern Ireland
- Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon
- Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature
- Use of prescribed contraception in Northern Ireland 2010-2016
- Using a patient prompt list to raise concerns in oncology clinics does not necessarily lead to longer consultations
- Using computer, mobile and wearable technology enhanced interventions to reduce sedentary behaviour: a systematic review and meta-analysis
- Using Mobile Technology to Provide Personalized Reminiscence for People Living With Dementia and Their Carers: Appraisal of Outcomes From a Quasi-Experimental Study
- Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival
- Vitamin D Deficiency Is Associated With Inflammation in Older Irish Adults
- Vitamin D3 supplementation in healthy adults: a comparison between capsule and oral spray solution as a method of delivery in a wintertime, randomised, open-label, cross-over study
- Vitamin D3 supplementation using an oral spray solution resolves deficiency but has no effect on VO2 max in Gaelic footballers: results from a randomised, double-blind, placebo-controlled trial
- Walking Exercise for Chronic Musculoskeletal Pain: Systematic Review and Meta-Analysis
- 'When it faded in her ... it faded in me' : A qualitative study exploring the impact of care-giving on the experience of spousal intimacy for older male care-givers
- WHO World Mental Health Surveys International College Student Project: Prevalence and Distribution of Mental Disorders
- Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2